Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
| ▸ | FDPS | P14324 | 9/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556929 | 0.98 | SMN1; SMN2 (0.32) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL29105772 | 0.82 | DNM1 (0.37) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL1405559 | 0.79 | TSHR (0.38) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL1973324 | 0.79 | TSHR (0.38) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL11861395 | 0.77 | LMNA (0.40) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL593280 | 0.77 | LMNA (0.40) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL28194942 | 0.77 | LMNA (0.40) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL1227633 | 0.76 | DNM1 (0.35) | TSHRALDH1A1FDPS | |
| SCHEMBL1971096 | 0.76 | TSHR (0.33) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL28674433 | 0.74 | TSHR (0.38) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808172-A | Pulmonary monisin B0Derivatives, preparation method and application thereof | 上海森辉医药有限公司 | 2020-10-23 | — | — | CN | disclosed |