Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082563 | 0.85 | AKR1C1 (0.50) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL4456359 | 0.85 | AKR1C1 (0.50) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL28470093 | 0.81 | CYP19A1 (0.43) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL16946606 | 0.79 | CYP19A1 (1.00) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL28467868 | 0.78 | KIF11 (0.46) | CYP19A1CYP11B2 | |
| SCHEMBL28465085 | 0.77 | KIF11 (0.47) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL22460011 | 0.73 | CYP19A1 (0.50) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL5586432 | 0.73 | CYP19A1 (0.61) | CYP19A1CYP11B2KMT2AMEN1MAPT | |
| SCHEMBL9804583 | 0.73 | MAPT (0.56) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL13659547 | 0.72 | MAPT (0.59) | CYP19A1CYP11B2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675650-B | Preparation method of aromatic vinyl bromide derivative | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2021-09-03 | — | — | CN | disclosed |
| CN-111675650-A | Preparation method of aromatic vinyl bromide derivative | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2020-09-18 | — | — | CN | disclosed |