Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456359 | 1.00 | AKR1C1 (0.50) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL28465740 | 0.85 | CYP19A1 (0.66) | AKR1C1FBP1CYP19A1CYP11B2LMNA | |
| SCHEMBL28465290 | 0.80 | ALDH1A1 (0.58) | FBP1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9805619 | 0.78 | TSHR (0.58) | AKR1C3LMNAMAPTALDH1A1HTT | |
| SCHEMBL3911150 | 0.76 | AKR1C3 (0.52) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL180460 | 0.76 | AKR1C3 (0.52) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL13997261 | 0.76 | AKR1C3 (0.52) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL16933770 | 0.74 | CES2 (0.39) | MAPTALDH1A1MEN1POLBMAPK1 | |
| SCHEMBL389392 | 0.74 | AKR1C1 (0.54) | AKR1C1AKR1C3PRMT1ESR1CYP19A1 | |
| SCHEMBL11365790 | 0.74 | CES2 (0.39) | MAPTALDH1A1MEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539079-A | Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in super-stable electrochromic material | 吉林大学 | 2022-05-27 | — | — | CN | claimed |
| CN-106187780-A | A kind of diphenyl ethylene derivatives with nitric oxide donors and preparation method thereof | 山东省医学科学院药物研究所 | 2016-12-07 | — | — | CN | claimed |
| CN-101967086-A | Alkoxy-contained conjugated brominated stilbene type sensitizing agent as well as synthesis and application thereof | UNIV CHONGQING | 2011-02-09 | — | — | CN | claimed |
| US-4713421-A | ADDING POLYMERIZATION INHIBITOR AT 60 TO 95% CONVERSION | STANDARD OIL COMPANY (INDIANA) (US) | 1987-12-15 | — | — | US | claimed |
| CN-114539079-A | Diamine monomer containing tetraphenylethylene-diarylamine structure, preparation method and application of diamine monomer in super-stable electrochromic material | 吉林大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-110256192-A | It is a kind of using alcohol be hydrogen source Photocatalysis selectivity synthesis cis and trans olefins process | 南通大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-110218141-A | A kind of Photocatalysis selectivity synthesis Z- and E- olefins process | 南通大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-109134172-A | The alcohol hydrogen supply iridium catalytic selectivity of ligand regulation synthesizes Z- and E- olefins process | 南通大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-106187780-A | A kind of diphenyl ethylene derivatives with nitric oxide donors and preparation method thereof | 山东省医学科学院药物研究所 | 2016-12-07 | — | — | CN | disclosed |
| CN-103724319-B | The preparation method of a kind of benzothiophenes and purification method thereof | 温州大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-104926837-A | Heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL | 2015-09-23 | — | — | CN | disclosed |
| CN-103180326-B | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL | 2015-06-10 | — | — | CN | disclosed |
| CN-101967086-A | Alkoxy-contained conjugated brominated stilbene type sensitizing agent as well as synthesis and application thereof | UNIV CHONGQING | 2011-02-09 | — | — | CN | disclosed |
| EP-1592698-B1 | PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF | TAKASAGO PERFUMERY CO LTD (JP) | 2008-03-26 | — | — | EP | disclosed |
| US-7129367-B2 | Phosphine compound, its intermediate, its complex with palladium and a manufacturing method of unsaturated compounds by using the palladium complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20060058542-A1 | Phosphine compound, its intermediate, its complex with palladium and a manufacturing method of unsaturated compounds by using the palladium complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1592698-A2 | PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF | Takasago International Corporation (JP) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072088-A2 | PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |
| US-5501804-A | Apparatus and process for blending elastomer particles and solution into a uniform mixture | AMOCO CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-4713421-A | ADDING POLYMERIZATION INHIBITOR AT 60 TO 95% CONVERSION | STANDARD OIL COMPANY (INDIANA) (US) | 1987-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058542-A1 | Phosphine compound, its intermediate, its complex with palladium and a manufacturing method of unsaturated compounds by using the palladium complex | SQLE, C9, PHOSPHO1 | AKR1C1 2123/4885FBP1 2149/4885AKR1C3 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.