SCHEMBL28466754

SCHEMBL28466754

CCCCCCC1CN1S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
GRM2 Q14416 1/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MCHR1 Q99705 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MMP2 P08253 1/20 0.43
POLB P06746 1/20 0.42
PSEN1 P49768 1/20 0.41
PSEN2 P49810 1/20 0.41
APH1B Q8WW43 1/20 0.41
NCSTN Q92542 1/20 0.41
APH1A Q96BI3 1/20 0.41
PSENEN Q9NZ42 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6081707 1.00 ALDH1A1 (0.44) ALDH1A1LMNAKMT2AGRM2MCOLN3
SCHEMBL8472978 1.00 ALDH1A1 (0.44) ALDH1A1LMNAKMT2AGRM2MCOLN3
SCHEMBL2600496 0.94 ALDH1A1 (0.46) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1
SCHEMBL11991815 0.88 PSEN1 (0.51) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1
SCHEMBL9877823 0.86 KMT2A (0.55) ALDH1A1LMNAKMT2ANPSR1POLB
SCHEMBL6526840 0.85 ALDH1A1 (0.57) ALDH1A1LMNAKMT2ANPSR1POLB
SCHEMBL29193737 0.84 MCOLN3 (0.40) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1
SCHEMBL29266630 0.82 MCOLN3 (0.41) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1
SCHEMBL6845965 0.82 ALDH1A1 (0.50) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1
SCHEMBL6845966 0.82 ALDH1A1 (0.50) ALDH1A1LMNAKMT2AMCOLN3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111675806-B Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative 上海交通大学 2022-01-11 CN claimed
CN-111675806-A Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative 上海交通大学 2020-09-18 CN claimed
CN-111675806-B Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative 上海交通大学 2022-01-11 CN disclosed
CN-111675806-A Air atmosphere anion ring-opening polymerization method of N-sulfonyl aziridine derivative 上海交通大学 2020-09-18 CN disclosed