Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526840 | 0.98 | ALDH1A1 (0.57) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL28466754 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAPKMPOLB | |
| SCHEMBL8472978 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAPKMPOLB | |
| SCHEMBL6081707 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAPKMPOLB | |
| SCHEMBL9485554 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL2600496 | 0.81 | ALDH1A1 (0.46) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL8205234 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL5556846 | 0.79 | GAA (0.52) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL8192516 | 0.77 | GAA (0.55) | KMT2AALDH1A1LMNAPKMHTT | |
| SCHEMBL9273582 | 0.75 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049667-A | Nitrogen-containing cyclic ligands | GUERBET S.A. (FR) | 1991-09-17 | — | — | US | disclosed |