Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464477 | 0.78 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8048033 | 0.75 | SMN1; SMN2 (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL10224151 | 0.75 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8057068 | 0.75 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL7301504 | 0.75 | HTT (0.71) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL2728938 | 0.74 | TDP1 (0.46) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL2728943 | 0.74 | TDP1 (0.46) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5455180 | 0.70 | GAA (0.64) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9837193 | 0.70 | GAA (0.60) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28469510 | 0.70 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777526-A | N-benzoylaniline derivatives, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-16 | — | — | CN | claimed |
| CN-111777526-A | N-benzoylaniline derivatives, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-16 | — | — | CN | disclosed |