Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25349869 | 0.83 | MEN1 (0.65) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8048033 | 0.81 | SMN1; SMN2 (0.58) | MAPTGAAMEN1KMT2APABPC1 | |
| SCHEMBL10224151 | 0.81 | MAPT (0.58) | MAPTGAAMEN1KMT2APABPC1 | |
| SCHEMBL8057068 | 0.81 | MAPT (0.58) | MAPTGAAMEN1KMT2APABPC1 | |
| SCHEMBL7301504 | 0.80 | HTT (0.71) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL14351715 | 0.78 | KCNMA1 (0.78) | MAPTGAAMEN1KMT2ACXCR1 | |
| SCHEMBL28467006 | 0.78 | MAPT (0.55) | MAPTGAAMEN1KMT2APABPC1 | |
| SCHEMBL9837193 | 0.78 | GAA (0.60) | MAPTGAAMEN1KMT2ACXCR1 | |
| SCHEMBL5455180 | 0.78 | GAA (0.64) | MAPTGAAMEN1KMT2ACXCR1 | |
| SCHEMBL28467905 | 0.78 | TTR (0.56) | MAPTMEN1KMT2ATDP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777526-A | N-benzoylaniline derivatives, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-16 | — | — | CN | claimed |
| CN-111777526-A | N-benzoylaniline derivatives, preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-16 | — | — | CN | disclosed |