Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059547 | 0.85 | HTT (0.58) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL10224151 | 0.85 | MAPT (0.58) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL8057068 | 0.83 | MAPT (0.58) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL28464477 | 0.81 | MAPT (0.64) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL7301504 | 0.80 | HTT (0.71) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL5648998 | 0.77 | HTT (0.80) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL14351715 | 0.76 | KCNMA1 (0.78) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL5455180 | 0.76 | GAA (0.64) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL6260473 | 0.76 | NPC1 (0.70) | SMN1; SMN2HTTMAPTKMT2AMEN1 | |
| SCHEMBL28467006 | 0.75 | MAPT (0.55) | SMN1; SMN2HTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032749-A2 | SALICYLANILIDE MODIFIED PEPTIDES FOR USE AS ORAL THERAPEUTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNINA (US) | 2009-03-12 | — | — | WO | disclosed |