SCHEMBL28467280

SCHEMBL28467280

COCCC1=CC(CCOC)c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.50
ADRB2 P07550 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6466704 0.77 HTR6 (0.35) HTR6ADRB2TSHR
SCHEMBL6466706 0.75 HTR6 (0.34) HTR6ADRB2
SCHEMBL7455581 0.75 HTR6 (0.54) HTR6
SCHEMBL28003598 0.71 HTR6 (0.50) HTR6
SCHEMBL27461742 0.69 HTR6 (0.48) HTR6
SCHEMBL6067259 0.69 HTR6 (0.40) HTR6
SCHEMBL8031035 0.67 HTR6 (0.39) HTR6
SCHEMBL7624281 0.65 HTR6 (0.47) HTR6
SCHEMBL6355109 0.65 HTR6 (0.44) HTR6
SCHEMBL27484008 0.65 HTR6 (0.46) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066263-A Directed conjugation techniques 克莱奥药品有限公司 2022-09-16 CN disclosed
CN-108137492-B Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2021-12-21 CN disclosed
CN-113398126-A Use of 4' -deferthionin analogues 佛罗里达大学研究基金会 2021-09-17 CN disclosed
CN-113278617-A Chiral design 波涛生命科学有限公司 2021-08-20 CN disclosed
CN-106068325-B Chiral design 波涛生命科学有限公司 2021-07-09 CN disclosed
CN-104114170-B Use of 4' -deferthionin analogues 佛罗里达大学研究基金会 2021-07-06 CN disclosed
CN-111848940-A Polycarbonate polyol compositions and methods 沙特阿美技术公司 2020-10-30 CN disclosed
CN-107266669-B Polycarbonate polyol compositions and methods 沙特阿美技术公司 2020-08-25 CN disclosed