Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390709 | 0.92 | MTNR1A (0.38) | GABRA1GABRB2ELANEMTNR1AMTNR1B | |
| SCHEMBL17088070 | 0.88 | MTNR1A (0.39) | GABRA1GABRB2ELANEMTNR1AMTNR1B | |
| SCHEMBL27996128 | 0.85 | MTNR1A (0.41) | ELANEMTNR1AMTNR1BNPC1MAPT | |
| SCHEMBL21862217 | 0.81 | ELANE (0.50) | GABRA1GABRB2ELANEMTNR1AMTNR1B | |
| SCHEMBL5542360 | 0.81 | F2RL3 (0.45) | ELANEGAANPC1MAPTRAB9A | |
| SCHEMBL24785491 | 0.80 | ELANE (0.51) | GABRA1GABRB2ELANENPC1MAPT | |
| SCHEMBL1917749 | 0.80 | ELANE (0.39) | ELANEGAANPC1MAPTRAB9A | |
| SCHEMBL27418773 | 0.80 | ELANE (0.39) | GABRA1GABRB2ELANEMAPTALDH1A1 | |
| SCHEMBL5542354 | 0.80 | MAPT (0.35) | MTNR1AMTNR1BGAANPC1MAPT | |
| SCHEMBL6962816 | 0.80 | ACHE (0.39) | GABRA1GABRB2GAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558786-B | Lubricating oil antifriction and antiwear additive and application thereof | 武汉工程大学 | 2020-09-25 | — | — | CN | disclosed |