SCHEMBL28468129

SCHEMBL28468129

CCCCCCCCc1nnnc(NCCCC)c1CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 20/20 0.48
TLR7 Q9NYK1 10/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440580 0.78 TYR (0.37) TLR8TLR7
SCHEMBL28572772 0.72 ALDH1A1 (0.35)
SCHEMBL1639820 0.70 TLR8 (0.41) TLR8TLR7
SCHEMBL3265562 0.68 MEN1 (0.39)
SCHEMBL13329924 0.65 TLR8 (0.63) TLR8TLR7
SCHEMBL20434283 0.65 TLR8 (1.00) TLR8TLR7
SCHEMBL4721365 0.65 TLR8 (0.40) TLR8TLR7
SCHEMBL11667441 0.65 TLR8 (0.41) TLR8TLR7
SCHEMBL10815142 0.65 TLR8 (0.41) TLR8TLR7
SCHEMBL113502 0.64 ALDH1A1 (0.46) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113226362-A Topical formulations for delivery of microbially-derived materials 马特里西斯生物科学公司 2021-08-06 CN disclosed
CN-111801108-A Topical skin care compositions 斯金基克有限责任公司 2020-10-20 CN disclosed