SCHEMBL440580

SCHEMBL440580

CCCCCc1nnnc(CCCCC)c1CCCCC

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
KCNH2 Q12809 1/20 0.34
NPC1 O15118 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
TYMP P19971 3/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
HSD11B1 P28845 1/20 0.33
GCGR P47871 1/20 0.33
CACNA2D1 P54289 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27796942 0.93 NPSR1 (0.40) TYRALDH1A1NPSR1NPC1HPGD
SCHEMBL28572772 0.83 ALDH1A1 (0.35) MEN1KMT2ATDP1L3MBTL1ALDH1A1
SCHEMBL3265562 0.82 MEN1 (0.39) MEN1KMT2ATDP1L3MBTL1ALDH1A1
SCHEMBL28468129 0.78 TLR8 (0.48) TLR8TLR7
SCHEMBL5138094 0.77 NPC1 (0.43) MEN1KMT2AALDH1A1NPSR1NPC1
SCHEMBL1187263 0.76 MEN1 (0.40) TYRMEN1KMT2ATDP1L3MBTL1
SCHEMBL1187583 0.74 ALDH1A1 (0.42) TYRMEN1KMT2AALDH1A1KCNH2
SCHEMBL1187104 0.74 ALDH1A1 (0.42) TYRMEN1KMT2AALDH1A1KCNH2
SCHEMBL1189782 0.74 ALDH1A1 (0.42) TYRMEN1KMT2AALDH1A1KCNH2
SCHEMBL1188376 0.74 MEN1 (0.35) TYRMEN1KMT2ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211056-B1 COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES CDT OXFORD LTD (GB) 2020-07-22 EP claimed
EP-2435017-B1 BENZYLIDENE MALONATES BASF SE (DE) 2019-10-23 EP claimed
EP-3137296-B1 MULTI-LAYERED FILM AND THE USE THEREOF BASF SE (DE) 2018-08-01 EP claimed
EP-2057249-B1 COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES CDT OXFORD LTD (GB) 2017-11-08 EP claimed
US-9680110-B2 Compounds for use in opto-electrical devices CDT OXFORD LIMITED (GB) 2017-06-13 US claimed
US-20140335638-A1 Compounds for Use in Opto-Electrical Devices CDT OXFORD LIMITED (GB) 2014-11-13 US claimed
EP-2069830-B1 ULTRAVIOLET LIGHT ABSORBING OPTICAL ELEMENTS AND COMPOSITIONS AND METHODS FOR MANUFACTURE CARL ZEISS VISION AU HOLDING (AU) 2012-08-29 EP claimed
US-20120128745-A1 BENZYLIDENE MALONATES BASF SE (DE) 2012-05-24 US claimed
EP-2258759-A1 Compositions for Preventing the Photodecomposition CYTEC TECHNOLOGY CORP. (US) 2010-12-08 EP claimed
EP-1080147-B2 METHODS AND COMPOSITIONS FOR PROTECTING POLYMERS FROM UV LIGHT CYTEC TECH CORP (US) 2010-12-01 EP claimed
JP-2007507567-A 2007-03-29 JP claimed
US-20060235116-A1 Highly compatible and non-migratory polymeric uv-absorber CIBA SPECIALTY CHEMICALS CORP. 2006-10-19 US claimed
EP-1627011-A2 HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER Ciba SC Holding AG (CH) 2006-02-22 EP claimed
EP-1274784-B1 LIGHT STABLE ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2005-10-19 EP claimed
EP-1481024-B1 UV STABILIZED THERMOPLASTIC OLEFINS CYTEC TECH CORP (US) 2005-07-13 EP claimed
US-20040241111-A1 Highly compatible hydroxyphenyltriazine uv-absorbers CIBA SPECIALTY CHEMICALS CORP. 2004-12-02 US claimed
WO-2004104081-A2 HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-12-02 WO claimed
EP-1080147-B1 METHODS AND COMPOSITIONS FOR PROTECTING POLYMERS FROM UV LIGHT CYTEC TECH CORP (US) 2004-11-10 EP claimed
EP-1401942-A1 HIGHLY COMPATIBLE HYDROXYPHENYLTRIAZINE UV-ABSORBERS Ciba SC Holding AG (CH) 2004-03-31 EP claimed
WO-2003004557-A1 HIGHLY COMPATIBLE HYDROXYPHENYLTRIAZINE UV-ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-01-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128745-A1 BENZYLIDENE MALONATES TERT, REL, MGMT TYR 90/4885MEN1 120/4885KMT2A 4071/4885
US-20040241111-A1 Highly compatible hydroxyphenyltriazine uv-absorbers TYR, HAAO, HTT TYR 1/4885MEN1 2757/4885KMT2A 2347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.