Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475546 | 0.90 | MAPT (0.66) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL969392 | 0.88 | TRPV1 (0.72) | MAPTLMNABAZ2BKDM4EFAAH | |
| SCHEMBL3079170 | 0.87 | MAPT (0.71) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL28387618 | 0.87 | BAZ2B (1.00) | MAPTLMNABAZ2BTAAR1ALDH1A1 | |
| SCHEMBL14015615 | 0.87 | MAPT (0.75) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL16462808 | 0.87 | MAPT (0.75) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL30228505 | 0.86 | MAPT (0.61) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL31228651 | 0.85 | TAAR1 (0.72) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL21243082 | 0.85 | MAPT (0.76) | MAPTLMNABAZ2BTAAR1GAA | |
| SCHEMBL21222687 | 0.85 | TAAR1 (0.72) | MAPTLMNABAZ2BTAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195500-A1 | A PROCESS FOR THE PREPARATION OF LUMATEPERONE TOSYLATE INTERMEDIATE | AMI ORGANICS LTD. (IN) | 2022-09-22 | — | — | WO | claimed |
| CN-109928971-B | Aryl substituted aminotetrahydropyrans and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-111757882-B | Compounds for treating, alleviating or preventing conditions associated with tau aggregates | AC免疫有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022195500-A1 | A PROCESS FOR THE PREPARATION OF LUMATEPERONE TOSYLATE INTERMEDIATE | AMI ORGANICS LTD. (IN) | 2022-09-22 | — | — | WO | disclosed |
| CN-111757882-A | 1,3,4, 5-tetrahydro-2H-pyrido [4,3-b ] indole derivatives for the treatment, alleviation or prevention of disorders associated with Tau aggregates such as alzheimer's disease | AC免疫有限公司 | 2020-10-09 | — | — | CN | disclosed |