SCHEMBL284688

SCHEMBL284688

COC(=O)C(C)(C)SSC(C)(C)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.44
ALDH1A1 P00352 2/20 0.35
KCNN4 O15554 1/20 0.34
SRC P12931 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10806114 0.80
SCHEMBL6229415 0.76 DGAT1 (0.39) DGAT1ALDH1A1KCNN4TSHR
SCHEMBL11444676 0.74 DGAT1 (0.38) DGAT1ALDH1A1KCNN4SRCTSHR
SCHEMBL13313610 0.74 DGAT1 (0.38) DGAT1KCNN4TSHR
SCHEMBL2602836 0.72 DGAT1 (0.37) DGAT1
SCHEMBL13450120 0.72 DGAT1 (0.37) DGAT1
SCHEMBL808799 0.71 DGAT1 (0.74) DGAT1ALDH1A1KCNN4SRCKEAP1
SCHEMBL1424791 0.71 DGAT1 (0.50) DGAT1ALDH1A1KCNN4SRCKEAP1
SCHEMBL15139 0.71
SCHEMBL4328011 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592356-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2013-11-26 US claimed
US-8309499-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2012-11-13 US claimed
US-20210214637-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-15 US disclosed
EP-3795663-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2021-03-24 EP disclosed
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-20160257902-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2016-09-08 US disclosed
EP-3064564-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-09-07 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
US-9139795-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-09-22 US disclosed
EP-2428552-B1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2015-07-01 EP disclosed
US-8987177-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-03-24 US disclosed
US-20100144567-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-10 US disclosed
EP-2157160-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed
US-20100009882-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD (JP) 2010-01-14 US disclosed
US-20100009880-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2010-01-14 US disclosed
US-20090203561-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2009-08-13 US disclosed
EP-2077319-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2009-07-08 EP disclosed
EP-2067846-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2009-06-10 EP disclosed
EP-2060619-A1 LUBRICANT COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2009-05-20 EP disclosed
US-20060148663-A1 Additives for lubricating oils and fuel oils, lubricating oil compositions, and fuel oil compositions IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed