Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161261 | 0.67 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL22638823 | 0.65 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL22638907 | 0.65 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL22638820 | 0.65 | RIPK1 (0.51) | RIPK1 | |
| SCHEMBL21797971 | 0.64 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL2629282 | 0.59 | DDB1 (0.36) | — | |
| SCHEMBL82304 | 0.59 | — | — | |
| SCHEMBL20580062 | 0.58 | ALDH1A1 (0.32) | RIPK1 | |
| SCHEMBL20411827 | 0.56 | BACE1 (0.33) | — | |
| SCHEMBL31520440 | 0.56 | UHRF1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370452-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107624111-B | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-11-03 | — | — | CN | disclosed |