Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477567 | 0.98 | HPGD (0.51) | HPGDMAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28474544 | 0.98 | HPGD (0.51) | HPGDMAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28474571 | 0.98 | HPGD (0.51) | HPGDMAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL21605354 | 0.94 | HPGD (0.54) | HPGDMAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28900462 | 0.89 | HPGD (0.56) | HPGDMAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL20121232 | 0.85 | MAPT (0.53) | HPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL14722425 | 0.81 | CES2 (0.54) | ALDH1A1HSD17B10PPARGPPARACES2 | |
| SCHEMBL29060487 | 0.81 | CES2 (0.54) | ALDH1A1HSD17B10PPARGPPARACES2 | |
| SCHEMBL21357337 | 0.81 | TP53 (0.53) | MAPTALDH1A1HSD17B3 | |
| SCHEMBL28294801 | 0.81 | TPSAB1 (0.40) | MAPTALDH1A1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | claimed |
| CN-109796383-B | 1-thiophenyl-N-acetyl-2-naphthylamine and its derivative and synthesis method | 湘潭大学 | 2020-09-18 | — | — | CN | disclosed |