Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 14/20 | 0.49 |
| ▸ | TCF7L2 | Q9NQB0 | 14/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469466 | 0.94 | CTNNB1 (0.56) | CTNNB1TCF7L2 | |
| SCHEMBL28462522 | 0.84 | MAPT (0.47) | MAPTBLMNPSR1TDP1L3MBTL1 | |
| SCHEMBL28462520 | 0.82 | CTNNB1 (0.58) | L3MBTL1SMN1; SMN2CTNNB1TCF7L2EGFR | |
| SCHEMBL28469365 | 0.80 | SMN1; SMN2 (0.56) | MAPTBLMNPSR1TDP1L3MBTL1 | |
| SCHEMBL28465329 | 0.79 | CYP1A2 (0.49) | MAPTL3MBTL1SMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL28463573 | 0.78 | LMNA (0.48) | MAPTSMN1; SMN2MAPK1EGFR | |
| SCHEMBL28459657 | 0.78 | EGFR (0.47) | MAPTL3MBTL1SMN1; SMN2CTNNB1TCF7L2 | |
| SCHEMBL28460390 | 0.78 | EGFR (0.55) | MAPTL3MBTL1SMN1; SMN2MAPK1EGFR | |
| SCHEMBL28462704 | 0.74 | BRD4 (0.42) | MAPTTDP1L3MBTL1SMN1; SMN2CTNNB1 | |
| SCHEMBL28462514 | 0.73 | HTT (0.47) | MAPTL3MBTL1CTNNB1TCF7L2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522659-B | 3-nitroquinoline derivative and preparation method and application thereof | 云南大学 | 2020-09-29 | — | — | CN | disclosed |