Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15824404 | 0.92 | PLK1 (0.49) | PLK1THRBALDH1A1PPARAKMT2A | |
| SCHEMBL4264438 | 0.82 | GAA (0.43) | PLK1SMN1; SMN2SENP8SENP7SENP6 | |
| SCHEMBL57873 | 0.79 | GAA (0.43) | PLK1SMN1; SMN2SENP8SENP7SENP6 | |
| SCHEMBL76776 | 0.71 | PLK1 (0.49) | PLK1THRBALDH1A1 | |
| SCHEMBL1100625 | 0.71 | BLM (0.58) | PLK1SMN1; SMN2THRBALDH1A1POLB | |
| SCHEMBL3758445 | 0.71 | THRB (0.46) | PLK1SMN1; SMN2SENP8SENP7SENP6 | |
| SCHEMBL1592157 | 0.70 | CYP3A4 (0.54) | PLK1SMN1; SMN2RAB9ATHRBALDH1A1 | |
| SCHEMBL7607626 | 0.70 | ITGB1 (0.51) | PLK1ALDH1A1GAAKDM4EPOLB | |
| SCHEMBL29045013 | 0.70 | BLM (0.56) | PLK1SMN1; SMN2RAB9ATHRBALDH1A1 | |
| SCHEMBL57370 | 0.69 | PLK1 (0.56) | PLK1MAPTTHRBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712523-A | Ophthalmic product composition | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | disclosed |