SCHEMBL57370

SCHEMBL57370

CCCCCCCCc1ccc(P(=O)(C(=O)c2c(Cl)cccc2Cl)C(=O)c2c(Cl)cccc2Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 3/20 0.56
ENPP2 Q13822 1/20 0.48
THRA P10827 2/20 0.46
THRB P10828 2/20 0.46
EP300 Q09472 1/20 0.45
KAT5 Q92993 1/20 0.45
KAT8 Q9H7Z6 1/20 0.45
ALDH1A1 P00352 3/20 0.43
S1PR1 P21453 2/20 0.43
S1PR3 Q99500 2/20 0.43
S1PR4 O95977 1/20 0.43
S1PR5 Q9H228 1/20 0.43
ESR1 P03372 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
PLK3 Q9H4B4 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76776 0.95 PLK1 (0.49) PLK1ENPP2THRATHRBEP300
SCHEMBL57873 0.89 GAA (0.43) PLK1THRBALDH1A1KDM4EMAPT
SCHEMBL28681426 0.82 PLK1 (0.57) PLK1ENPP2EP300KAT5KAT8
SCHEMBL29115346 0.78 PPARA (0.46) PLK1THRATHRBEP300KAT5
Ammonia Solution, Strong SCHEMBL28944620 0.76 RARB (0.55) PLK1THRATHRBALDH1A1PLK3
SCHEMBL15824404 0.75 PLK1 (0.49) PLK1ENPP2THRATHRBALDH1A1
SCHEMBL20742745 0.75 TAS1R3 (0.45) PLK1ALDH1A1KDM4ELMNAMAPT
SCHEMBL7622733 0.75 PLK1 (0.44) PLK1ALDH1A1MEN1MAPTKMT2A
SCHEMBL2769886 0.75 PLK1 (0.44) PLK1ALDH1A1MEN1MAPTKMT2A
SCHEMBL58428 0.75 PLK1 (0.44) PLK1ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US claimed
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP claimed
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
EP-4286163-B1 ELECTRON BEAM CURABLE INK, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2026-04-01 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4681930-A1 IMAGE RECORDING METHOD, METHOD FOR MANUFACTURING LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-20250375971-A1 IMAGE RECORDING METHOD, MANUFACTURING METHOD OF LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM CORP (JP) 2025-12-11 US disclosed
EP-4660262-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK, ACTIVE ENERGY RAY-CURABLE INK SET, AND IMAGE RECORDING METHOD FUJIFILM Corporation (JP) 2025-12-10 EP disclosed
US-20250340747-A1 ACTIVE ENERGY RAY CURABLE TYPE INK JET INK, ACTIVE ENERGY RAY CURABLE TYPE INK SET, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2025-11-06 US disclosed
US-20050221210-A1 Electrophotographic photoconductor and image formation method, image formation apparatus, and process cartridge for image formation apparatus using the electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2005-10-06 US disclosed
US-20040235980-A1 Polymerizable compound, polymerizable composition and cured product containing the compound SHOWA DENKO K.K. (JP) 2004-11-25 US disclosed
WO-2003010124-A1 POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND SHOWA DENKO K. K. (JP) 2003-02-06 WO disclosed
EP-0825201-B1 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2002-02-27 EP disclosed
EP-1044777-A1 Molding method for corrosion-resistant FRP SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-10-18 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A PLK1 1473/4885ENPP2 3556/4885THRA 244/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 PLK1 4309/4885ENPP2 3479/4885THRA 1528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.