Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487153 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL4844355 | 0.80 | — | — | |
| Propylene Glycol SCHEMBL10765776 | 0.75 | HSD17B10 (0.64) | TDP1HSD17B10USP2TSHR | |
| Propylene Glycol SCHEMBL56047 | 0.75 | HSD17B10 (0.64) | TDP1HSD17B10USP2TSHR | |
| SCHEMBL28818522 | 0.75 | USP2 (0.51) | USP2 | |
| Propylene Glycol SCHEMBL10613711 | 0.73 | HSD17B10 (0.61) | TDP1HSD17B10USP2TSHR | |
| Propylene Glycol SCHEMBL6390820 | 0.73 | TDP1 (0.53) | TDP1HSD17B10USP2TSHR | |
| Propylene Glycol SCHEMBL28092305 | 0.73 | HSD17B10 (0.61) | TDP1HSD17B10USP2TSHR | |
| SCHEMBL9903787 | 0.73 | — | — | |
| Propylene Glycol SCHEMBL2748505 | 0.71 | HSD17B10 (0.58) | TDP1HSD17B10USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111410711-B | Polymer composition comprising a crosslinked polymer having borate functional groups capable of undergoing an exchange reaction, preparation method and use | 巴黎市工业物理化学学校 | 2022-07-22 | — | — | CN | disclosed |
| CN-108473629-B | Polymer composition comprising a crosslinked polymer having borate functional groups capable of undergoing an exchange reaction, process for its preparation and use thereof | 巴黎市工业物理化学学校 | 2021-01-19 | — | — | CN | disclosed |
| CN-108368206-B | Polymer composition comprising a cross-linked polymer containing borate functional groups capable of undergoing an exchange reaction, process for its preparation and its use | 巴黎市工业物理化学学校 | 2020-09-08 | — | — | CN | disclosed |
| CN-111410711-A | Polymer composition comprising a crosslinked polymer having borate functional groups capable of undergoing an exchange reaction, preparation method and use | 巴黎市工业物理化学学校 | 2020-07-14 | — | — | CN | disclosed |