Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CCR7 | P32248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL10765776 | 1.00 | HSD17B10 (0.64) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL10613711 | 0.97 | HSD17B10 (0.61) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL28092305 | 0.97 | HSD17B10 (0.61) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL15353567 | 0.95 | HSD17B10 (0.58) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL3630707 | 0.93 | HSD17B10 (0.56) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL10406157 | 0.91 | TSHR (0.56) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL2748505 | 0.90 | HSD17B10 (0.58) | HSD17B10TDP1USP2TSHRHTT | |
| Propylene Glycol SCHEMBL23159801 | 0.89 | USP2 (0.62) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL122754 | 0.89 | HSD17B10 (0.52) | HSD17B10TDP1USP2TSHRMEN1 | |
| Propylene Glycol SCHEMBL445698 | 0.87 | HSD17B10 (0.50) | HSD17B10TDP1USP2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094997-A | Aqueous polyurethane coatings for printing applications | — | 2026-05-26 | — | — | CN | claimed |
| CN-122095027-A | Modified maleated natural oil-based reaction products and slurry compositions containing the same | — | 2026-05-26 | — | — | CN | claimed |
| US-12637616-B2 | Etching solution for selectively removing silicon-germanium alloy from a silicon-germanium/ silicon stack during manufacture of a semiconductor device | VERSUM MATERIALS US, LLC (US) | 2026-05-26 | — | — | US | claimed |
| CN-120464282-B | Composite hydrophobic phosphogypsum water-based building heat preservation coating and preparation method thereof | 中铁七局集团第五工程有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122055416-A | Dispersants for carbon nanotubes and carbon nanotube compositions comprising hydrophobically and hydrophilically modified maleated natural oil salts | 埃斯普投资有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-12624317-B2 | Method of reducing defects on polished wafers | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2026-05-12 | — | — | US | claimed |
| CN-122018256-A | Developing method, patterning method, and method for manufacturing electronic device | 珠海基石科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12604651-B2 | Rapid fabrication of semiconductor thin films | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-04-14 | — | — | US | claimed |
| EP-4335914-B1 | TEXTILE WASHING METHOD | HENKEL AG & CO KGAA (DE) | 2026-04-01 | — | — | EP | claimed |
| US-12590224-B2 | Chemical mechanical polishing compositions and methods of use thereof | FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) | 2026-03-31 | — | — | US | claimed |
| WO-1994003579-A1 | NONFLAMMABLE MILD ODOR SOLVENT CLEANER | LOCKHEED CORPORATION (US) | 1994-02-17 | — | — | WO | claimed |
| US-5149729-A | Protective coatings for wood | PPG INDUSTRIES, INC. (US) | 1992-09-22 | — | — | US | claimed |
| EP-0276772-B1 | PROCESS FOR THE MANUFACTURE OF MICRODISPERSE FISH OIL PREPARATIONS | BASF Aktiengesellschaft (DE) | 1992-07-15 | — | — | EP | claimed |
| US-4929533-A | Using light sensitive diazo resin and high molecular weight copolymer | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| US-4822514-A | Compositions and methods for cleaning surfaces while selectively imparting gloss or shine thereto | MURPHY-PHOENIX COMPANY (US) | 1989-04-18 | — | — | US | claimed |
| EP-0276772-A2 | Process for the manufacture of microdisperse fish oil preparations | BASF Aktiengesellschaft (DE) | 1988-08-03 | — | — | EP | claimed |
| EP-0205172-A2 | Zinc-based paints employing a mixture of ether alcohols as liquid organic vehicles | THE DOW CHEMICAL COMPANY (US) | 1986-12-17 | — | — | EP | claimed |
| US-4620873-A | Zinc-based paints employing a mixture of ether alcohols as liquid organic vehicle | THE DOW CHEMICAL COMPANY (US) | 1986-11-04 | — | — | US | claimed |
| EP-0065193-B1 | PROCESS FOR THE MANUFACTURE OF POWDERY, FINELY DIVIDED PREPARATIONS OF CAROTENOIDS OR RETINOIDS | BASF Aktiengesellschaft (DE) | 1985-12-04 | — | — | EP | claimed |
| US-4522743-A | HEATING PRESSURIZATION, QUICK-PROCESSING | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | claimed |