Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60402 | 0.79 | — | — | |
| Benzene SCHEMBL3509497 | 0.76 | PSIP1 (0.41) | TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28188004 | 0.75 | — | — | |
| Fluoride SCHEMBL27801850 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL29181623 | 0.75 | — | — | |
| Bicarbonate SCHEMBL27666585 | 0.75 | — | — | |
| Methylene Chloride SCHEMBL27633620 | 0.72 | — | — | |
| SCHEMBL10742898 | 0.72 | KDM4E (0.39) | CA1 | |
| Bicarbonate SCHEMBL9255781 | 0.72 | — | — | |
| Bicarbonate SCHEMBL29212811 | 0.72 | ALDH1A1 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111855904-A | Electrolyte waste gas detection device and application method thereof | 安徽南都华铂新材料科技有限公司 | 2020-10-30 | — | — | CN | disclosed |