Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 6/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410947 | 0.77 | TDP1 (0.34) | ALDH1A1MAPTKDM4EIRAK4 | |
| SCHEMBL6700799 | 0.74 | TSHR (0.48) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL29442763 | 0.74 | TSHR (0.48) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL19046335 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EIRAK4 | |
| SCHEMBL6764276 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EIRAK4TYR | |
| SCHEMBL19045852 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EIRAK4 | |
| SCHEMBL22404549 | 0.71 | CA12 (0.41) | ALDH1A1MAPTKDM4EIRAK4 | |
| SCHEMBL2558135 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4E | |
| SCHEMBL309778 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4E | |
| SCHEMBL19030770 | 0.69 | KMT2A (0.40) | ALDH1A1MAPTKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747919-B | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-111747919-A | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111747919-B | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-111747919-B | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-111747919-B | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-111747919-A | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111747919-A | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111747919-A | Direct preparation method of 5-hydroxy-2, 2-dimethyl-2H-benzofuran-6-formaldehyde | 上海沃凯生物技术有限公司 | 2020-10-09 | — | — | CN | disclosed |