SCHEMBL284700

SCHEMBL284700

c1ccc(Cc2ccc(Nc3ccc(Cc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.63
ALDH1A1 P00352 7/20 0.60
HSD17B10 Q99714 5/20 0.60
ALOX12 P18054 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
TSHR P16473 3/20 0.60
TDP1 Q9NUW8 3/20 0.60
ALOX15 P16050 2/20 0.60
MAPK1 P28482 2/20 0.60
PTGS1 P23219 1/20 0.60
SLC6A2 P23975 1/20 0.60
PTGS2 P35354 1/20 0.60
HTR2B P41595 1/20 0.60
SLC1A3 P43003 1/20 0.49
SLC1A2 P43004 1/20 0.49
SLC1A1 P43005 1/20 0.49
LTA4H P09960 1/20 0.48
CYP3A4 P08684 4/20 0.48
MAPT P10636 3/20 0.48
CYP2C9 P11712 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19187359 0.97 ALDH1A1 (0.65) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL25557237 0.97 ALDH1A1 (0.65) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL13308523 0.95 ALDH1A1 (0.68) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL8622727 0.95 ALDH1A1 (0.68) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL18416527 0.93 CALM1 (0.55) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
Diphenylmethane SCHEMBL2309364 0.92 HSD17B10 (0.67) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL9418470 0.91 CALM1 (0.52) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL28309142 0.89 HPGD (0.68) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
SCHEMBL17666367 0.88 ALDH1A1 (0.59) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1
Diphenylmethane SCHEMBL10780055 0.86 HPGD (0.71) CALM1ALDH1A1HSD17B10ALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326223-B1 Copolymer composition SHELL INT RESEARCH (NL) 1996-05-08 EP claimed
EP-0326223-A2 Copolymer composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-08-02 EP claimed
CN-109790300-B Semi-crystalline polyolefin-based additive masterbatch composition 陶氏环球技术有限责任公司 2022-09-13 CN disclosed
CN-109890878-B Semicrystalline polyolefin additive masterbatch composition 陶氏环球技术有限责任公司 2022-07-08 CN disclosed
CN-109890877-B Additive masterbatch composition based on semicrystalline polyolefins 陶氏环球技术有限责任公司 2022-06-28 CN disclosed
US-9139795-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-09-22 US disclosed
EP-2428552-B1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2015-07-01 EP disclosed
US-8987177-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-03-24 US disclosed
US-20140296117-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US disclosed
EP-2752480-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2014-07-09 EP disclosed
EP-2431450-B1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2014-05-07 EP disclosed
US-5019614-A Stabilized polymers SHELL OIL COMPANY (US) 1991-05-28 US disclosed
US-4992499-A Using phenolic compound and aromatic amine SHELL OIL COMPANY (US) 1991-02-12 US disclosed
EP-0395183-A1 Polyketone polymer compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-10-31 EP disclosed
US-4954548-A A DIPHENYLAMINE AND CARBON BLACK SHELL OIL COMPANY (US) 1990-09-04 US disclosed
EP-0326223-A2 Copolymer composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-08-02 EP disclosed
EP-0288124-A2 Stabilized copolymer compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-26 EP disclosed
EP-0089643-B1 IMPROVED POLYESTER TYPE BLOCK COPOLYMER COMPOSITION Toyo Boseki Kabushiki Kaisha (JP) 1985-12-27 EP disclosed
US-4500686-A CRYSTALLINE AROMATIC POLYESTERLACTONE COPOLYMER MELT-ADMIXED WITH EPOXY COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JP) 1985-02-19 US disclosed
EP-0089643-A2 Improved polyester type block copolymer composition Toyo Boseki Kabushiki Kaisha (JP) 1983-09-28 EP disclosed