SCHEMBL28470985

SCHEMBL28470985

CC(C)CCCCCCCS(=O)(=O)CCCCCCCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
CA2 P00918 2/20 0.38
FUT7 Q11130 1/20 0.36
CES1 P23141 4/20 0.35
KDM4C Q9H3R0 2/20 0.33
KDM4A O75164 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
TP53 P04637 1/20 0.32
BLM P54132 1/20 0.32
FAAH O00519 2/20 0.32
HIF1A Q16665 1/20 0.32
EPAS1 Q99814 1/20 0.32
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28939095 0.97 LMNA (0.46) LMNACA2FUT7CES1KDM4C
SCHEMBL441457 0.90 CA2 (0.40) LMNACA2FUT7CES1KDM4C
SCHEMBL17369606 0.89 LMNA (0.41) LMNACA2FUT7TP53BLM
SCHEMBL19002208 0.87 LMNA (0.42) LMNACA2FUT7CES1TP53
SCHEMBL439762 0.82 LMNA (0.42) LMNACA2FUT7KDM4CKDM4A
SCHEMBL8814285 0.82 LMNA (0.42) LMNACA2FUT7KDM4CKDM4A
SCHEMBL8811142 0.82 LMNA (0.42) LMNACA2FUT7KDM4CKDM4A
SCHEMBL18997082 0.81 LMNA (0.37) LMNACES1
SCHEMBL25358063 0.80 APP (0.42) LMNACA2FUT7KDM4CKDM4A
SCHEMBL5075273 0.80 LMNA (0.40) LMNACA2FUT7KDM4CKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715317-A Cyclic phosphonates for lubricant applications 路博润公司 2023-02-24 CN disclosed
CN-109952365-B Fluorinated polyacrylate defoamer component for lubricating compositions 路博润公司 2022-11-18 CN disclosed
CN-112105710-B Fluorinated polyacrylate antifoam in ultra low viscosity (< 5 CST) finished fluids 路博润公司 2022-08-30 CN disclosed
CN-112105710-A Novel fluorinated polyacrylate antifoam in ultra low viscosity (< 5 CST) finished fluids 路博润公司 2020-12-18 CN disclosed
CN-106459808-B Friction modifier mixtures providing good friction performance for transmission fluids 路博润公司 2020-10-27 CN disclosed