Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643347 | 0.85 | L3MBTL1 (0.49) | ALDH1A1HTTPBRM1TSHRHPGD | |
| SCHEMBL28474196 | 0.85 | L3MBTL1 (0.49) | ALDH1A1HTTPBRM1TSHRHPGD | |
| SCHEMBL27705148 | 0.83 | PBRM1 (0.43) | ALDH1A1HTTPBRM1TSHRHPGD | |
| SCHEMBL551671 | 0.82 | PBRM1 (0.42) | ALDH1A1HTTPBRM1TSHRHPGD | |
| SCHEMBL4919855 | 0.80 | TYK2 (0.55) | ALDH1A1HTTHPGDMAPK1MEN1 | |
| SCHEMBL18177833 | 0.78 | MEN1 (0.57) | ALDH1A1HTTTSHRHPGDMAPK1 | |
| SCHEMBL9963900 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HTTTSHRHPGDMEN1 | |
| SCHEMBL30431941 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HTTTSHRHPGDMEN1 | |
| SCHEMBL551795 | 0.77 | PBRM1 (0.49) | ALDH1A1PBRM1TSHRHPGDMEN1 | |
| SCHEMBL31356504 | 0.77 | TSHR (0.65) | ALDH1A1PBRM1TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808058-B | Fluorescent probe for screening drugs acting on ryanodine receptor | 天津大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-111808058-A | Fluorescent probe for screening drugs acting on ryanodine receptor | 天津大学 | 2020-10-23 | — | — | CN | disclosed |