Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.34 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472792 | 1.00 | CD274 (0.43) | CD274PDCD1ALDH1A1TLR2TLR1 | |
| SCHEMBL21622950 | 0.92 | CD274 (0.39) | CD274PDCD1ALDH1A1CTNNB1WNT3A | |
| SCHEMBL30340562 | 0.92 | CD274 (0.39) | CD274PDCD1ALDH1A1CTNNB1WNT3A | |
| SCHEMBL21616729 | 0.88 | CD274 (0.43) | CD274PDCD1ALDH1A1TLR2TLR1 | |
| SCHEMBL21616727 | 0.88 | CD274 (0.43) | CD274PDCD1ALDH1A1TLR2TLR1 | |
| SCHEMBL21622951 | 0.79 | ALDH1A1 (0.42) | CD274PDCD1ALDH1A1TLR2TLR1 | |
| SCHEMBL30340576 | 0.79 | ALDH1A1 (0.42) | CD274PDCD1ALDH1A1TLR2TLR1 | |
| SCHEMBL30340342 | 0.79 | PDCD1 (0.50) | CD274PDCD1 | |
| SCHEMBL21623099 | 0.77 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL28469231 | 0.76 | CD274 (0.45) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-A | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2020-11-03 | — | — | CN | disclosed |