SCHEMBL28473293

SCHEMBL28473293

CCC1Cc2ccccc2OC1([SiH3])CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.38
TSHR P16473 2/20 0.38
CYP2C19 P33261 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 1/20 0.38
PKM P14618 1/20 0.38
NFKB1 P19838 1/20 0.38
THPO P40225 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
LMNA P02545 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD11B1 P28845 1/20 0.33
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29008597 0.74 CYP1A2 (0.33) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL22325534 0.71 NFKB1 (0.35) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL9690440 0.69 SMN1; SMN2 (0.34) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL19289110 0.66 TSHR (0.38) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL19894302 0.66 CYP2D6 (0.38) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL9691750 0.66 HTR2A (0.37) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL3120050 0.65 CYP1A2 (0.35) CYP2D6TSHRCYP2C19CYP1A2PKM
SCHEMBL7790328 0.65 SIGMAR1 (0.37) CYP2D6TSHRCYP2C19NFKB1MEN1
SCHEMBL16797613 0.64 SIGMAR1 (0.40) CYP2D6TSHRCYP2C19SMN1; SMN2CYP1A2
SCHEMBL434338 0.64 HRH3 (0.49) AOC2MAOAMAOBCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001516-B Chromium-based catalyst composition for olefin polymerization 尤尼威蒂恩技术有限责任公司 2023-06-06 CN disclosed
CN-111690087-B Polyolefin production using chromium-based catalyst 尤尼威蒂恩技术有限责任公司 2023-05-26 CN disclosed
CN-112739731-A Unimodal polyethylene copolymer and film thereof 尤尼威蒂恩技术有限责任公司 2021-04-30 CN disclosed
CN-112585177-A Unimodal polyethylene copolymer and film thereof 尤尼威蒂恩技术有限责任公司 2021-03-30 CN disclosed
CN-111886261-A Polyethylene copolymer resin and film 尤尼威蒂恩技术有限责任公司 2020-11-03 CN disclosed