Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.67 |
| ▸ | CES1 | P23141 | 5/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187858 | 0.91 | CES2 (0.73) | CES2CES1PARP1TP53MEN1 | |
| SCHEMBL6670439 | 0.91 | PARP1 (0.68) | CES2CES1PARP1CYP1A2TP53 | |
| SCHEMBL4229652 | 0.89 | CES2 (0.61) | CES2CES1PARP1TP53ALDH1A1 | |
| SCHEMBL4524448 | 0.88 | CES2 (0.61) | CES2CES1PARP1CYP1A2TP53 | |
| SCHEMBL9125529 | 0.86 | CES2 (0.59) | CES2CES1PARP1CYP1A2CYP3A4 | |
| SCHEMBL3838117 | 0.83 | PARP1 (0.59) | PARP1CYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL13170586 | 0.82 | CES2 (0.59) | CES2CES1TP53ALDH1A1MEN1 | |
| SCHEMBL2657896 | 0.82 | MAPT (0.57) | CES2CES1PARP1CYP1A2CYP3A4 | |
| SCHEMBL649996 | 0.82 | CES2 (0.80) | CES2CES1TP53HPGDMEN1 | |
| SCHEMBL4110200 | 0.82 | PARP1 (0.49) | CES2CES1PARP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110343100-B | Phenothiazine co-sensitizer and preparation method and application thereof | 江苏理工学院 | 2020-10-30 | — | — | CN | claimed |
| CN-110343100-B | Phenothiazine co-sensitizer and preparation method and application thereof | 江苏理工学院 | 2020-10-30 | — | — | CN | disclosed |