Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.61 |
| ▸ | CES1 | P23141 | 5/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670439 | 0.93 | PARP1 (0.68) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL28473333 | 0.89 | CES2 (0.67) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL2684848 | 0.87 | PARP1 (0.61) | PARP1ALDH1A1TP53SMN1; SMN2HPGD | |
| SCHEMBL4524448 | 0.86 | CES2 (0.61) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL4204051 | 0.84 | CES2 (0.64) | CES2CES1PARP1ALDH1A1RAB9A | |
| SCHEMBL4847237 | 0.84 | CES2 (0.64) | CES2CES1PARP1ALDH1A1RAB9A | |
| SCHEMBL9125529 | 0.84 | CES2 (0.59) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL28771843 | 0.84 | PARP1 (0.53) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL2657896 | 0.84 | MAPT (0.57) | CES2CES1PARP1ALDH1A1TP53 | |
| SCHEMBL10410934 | 0.84 | CES2 (0.78) | CES2CES1ALDH1A1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3799143-B1 | FIRST AND SECOND ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | NOVALED GMBH (DE) | 2024-09-11 | — | — | EP | disclosed |
| EP-4035217-B1 | FIRST AND SECOND ORGANIC SEMICONDUCTOR LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | NOVALED GMBH (DE) | 2024-09-11 | — | — | EP | disclosed |
| CN-112368858-B | Organic material for electronic optoelectronic device and electronic device comprising the same | 诺瓦尔德股份有限公司 | 2024-08-02 | — | — | CN | disclosed |
| EP-3582280-B1 | ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL | NOVALED GMBH (DE) | 2024-03-20 | — | — | EP | disclosed |
| EP-3798213-B1 | ORGANIC SEMICONDUCTOR LAYER, ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME AND COMPOUNDS THEREFOR | NOVALED GMBH (DE) | 2024-01-10 | — | — | EP | disclosed |
| US-20230240136-A1 | First and Second Organic Semiconductor Layer and Organic Electronic Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230240136-A1 | First and Second Organic Semiconductor Layer and Organic Electronic Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230240136-A1 | First and Second Organic Semiconductor Layer and Organic Electronic Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-27 | — | — | US | disclosed |
| EP-3807941-B1 | ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL | NOVALED GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-3807941-B1 | ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL | NOVALED GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |
| US-20090176850-A1 | Novel 2-Amino-Imidazole-4-One Compounds And Their Use In The Manufacture Of A Medicament To Be Used In The Treatment Of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration And Dementia | ASTRAZENECA AB (SE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176850-A1 | Novel 2-Amino-Imidazole-4-One Compounds And Their Use In The Manufacture Of A Medicament To Be Used In The Treatment Of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration And Dementia | ASTRAZENECA AB (SE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176850-A1 | Novel 2-Amino-Imidazole-4-One Compounds And Their Use In The Manufacture Of A Medicament To Be Used In The Treatment Of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration And Dementia | ASTRAZENECA AB (SE) | 2009-07-09 | — | — | US | disclosed |
| US-20090093498-A1 | AMINO-5,5-DIPHENYLIMIDAZOLONE DERIVATIVES FOR THE INHIBITION OF BETA-SECRETASE | WYETH (US) | 2009-04-09 | — | — | US | disclosed |
| US-7482349-B2 | Amino-5,5-diphenylimidazolone derivatives for the inhibition of β-secretase | WYETH (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1954682-A1 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER S DISEASE, NEURODEGENERATION AND DEMENTIA | Astra Zeneca AB (SE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058601-A1 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058601-A1 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
| US-4071570-A | ANTIARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3978127-A | ANTIARRHYTHMIC | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176850-A1 | Novel 2-Amino-Imidazole-4-One Compounds And Their Use In The Manufacture Of A Medicament To Be Used In The Treatment Of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration And Dementia | PSEN2, MAPT, PSEN1 | CES2 2414/4885CES1 2700/4885PARP1 2812/4885 |
| US-20090093498-A1 | AMINO-5,5-DIPHENYLIMIDAZOLONE DERIVATIVES FOR THE INHIBITION OF BETA-SECRETASE | BACE1, BACE2, APP | CES2 3023/4885CES1 913/4885PARP1 2176/4885 |
| US-20230240136-A1 | First and Second Organic Semiconductor Layer and Organic Electronic Device Comprising the Same | OR10J3, AXIN2, POU2F1 | CES2 2797/4885CES1 4146/4885PARP1 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.