Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL315798 | 0.99 | HTR7 (0.33) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL315773 | 0.78 | GAA (0.39) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL2860313 | 0.78 | GAA (0.36) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL315719 | 0.78 | GAA (0.36) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL315896 | 0.76 | HTR7 (0.39) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL316500 | 0.71 | GAA (0.41) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL316150 | 0.71 | LMNA (0.42) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| Hydrochloric Acid SCHEMBL314663 | 0.70 | GAA (0.40) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL315609 | 0.69 | KDM1A (0.43) | HTR7HTR1AHTR2AGAAMCOLN3 | |
| SCHEMBL315076 | 0.69 | MEN1 (0.36) | HTR7HTR1AHTR2AGAAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831159-B1 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2010-01-20 | — | — | EP | claimed |