Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GPR183 | P32249 | 1/20 | 0.58 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631562 | 0.89 | HPGD (0.86) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL2534411 | 0.86 | HPGD (1.00) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL2535536 | 0.84 | HPGD (0.96) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5213430 | 0.83 | HPGD (0.93) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL10053023 | 0.83 | HPGD (0.75) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL7440364 | 0.81 | HPGD (0.73) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL2094842 | 0.81 | HPGD (0.73) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL26487595 | 0.81 | GPR183 (0.73) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL208986 | 0.81 | HPGD (0.73) | HPGDPOLBGAAALDH1A1L3MBTL1 | |
| SCHEMBL9792247 | 0.81 | HPGD (0.79) | HPGDPOLBGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370452-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107624111-B | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-11-03 | — | — | CN | disclosed |