Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | POLB | P06746 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | PHGDH | O43175 | 1/20 | 0.63 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631562 | 0.88 | HPGD (0.86) | HPGDPOLBALDH1A1L3MBTL1KMT2A | |
| Molracetam SCHEMBL2109861 | 0.87 | HPGD (0.65) | HPGDPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10720943 | 0.86 | PHGDH (0.81) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2534411 | 0.84 | HPGD (1.00) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28614894 | 0.84 | BLM (0.62) | HPGDPOLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6456595 | 0.83 | L3MBTL1 (0.73) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7422569 | 0.83 | HPGD (0.74) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15976788 | 0.83 | PHGDH (0.63) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2535536 | 0.83 | HPGD (0.96) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL19479126 | 0.82 | ALDH1A1 (0.83) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504653-A | Carboxylic acid amidation method | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | disclosed |
| CN-111574477-B | Synthesis method of amide compound | 湖南大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-111574477-A | Synthesis method of amide compound | 湖南大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-104321325-B | Pyrrolopyrrole alkanone compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |
| EP-2380891-A1 | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-4988822-A | Intermediates for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4873340-A | Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0053021-B1 | PROCESS FOR 5-AROYLATION OF 1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBOXYLIC ESTERS AND NITRILES | SYNTEX (U.S.A.) INC. (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4353829-A | AROYL MORPHOLIDE REAGENT | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0053021-A2 | Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole-1-carboxylic esters and nitriles | SYNTEX (U.S.A.) INC. (US) | 1982-06-02 | — | — | EP | disclosed |