SCHEMBL28474356

SCHEMBL28474356

CCCCCC(CC)OOC(=O)C=Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.47
HDAC3 O15379 2/20 0.44
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 2/20 0.43
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41
ALDH1A1 P00352 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119067 0.99 EGFR (0.49) EGFRHDAC3TDP1LMNATNKS
SCHEMBL119063 0.99 EGFR (0.49) EGFRHDAC3TDP1LMNATNKS
SCHEMBL3222440 0.87 EGFR (0.49) EGFRHDAC3TDP1LMNATNKS
SCHEMBL3222436 0.87 EGFR (0.49) EGFRHDAC3TDP1LMNATNKS
SCHEMBL119065 0.86 EGFR (0.51) EGFRHDAC3TDP1LMNATNKS
SCHEMBL21802303 0.84 EGFR (0.44) EGFRHDAC3TDP1LMNAAKR1B10
SCHEMBL21802302 0.84 EGFR (0.44) EGFRHDAC3TDP1LMNAAKR1B10
SCHEMBL28053687 0.82 EGFR (0.40) EGFRHDAC3TDP1LMNAAKR1B10
SCHEMBL119066 0.80 TDP1 (0.55) EGFRHDAC3TDP1LMNAAKR1B10
3-Octanol SCHEMBL28795848 0.80 EGFR (0.45) EGFRHDAC3TDP1LMNAAKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111840151-A Sunscreen agent 西安博和医疗科技有限公司 2020-10-30 CN disclosed