Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482515 | 0.89 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL19667207 | 0.88 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL22495027 | 0.82 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL22494872 | 0.82 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL28477494 | 0.82 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL24595461 | 0.79 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL19667605 | 0.77 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL19679322 | 0.76 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL30207970 | 0.76 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL19667148 | 0.76 | PRMT5 (0.43) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712498-A | Substituted bicyclic heterocyclic compounds as PRMT5 inhibitors | 鲁平有限公司 | 2020-09-25 | — | — | CN | disclosed |