SCHEMBL284751

SCHEMBL284751

CCCCCCCCCCc1ccccc1OP(=S)(Oc1ccccc1CCCCCCCCCC)Oc1ccccc1CCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.55
THRB P10828 1/20 0.55
LIPG Q9Y5X9 1/20 0.49
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
PPARA Q07869 2/20 0.47
PPARG P37231 1/20 0.47
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
BID P55957 3/20 0.39
MCL1 Q07820 3/20 0.39
BCL2L1 Q07817 2/20 0.39
BAK1 Q16611 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547923 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL8600594 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL31086340 1.00 THRA (0.55) THRATHRBLIPGALOX5PTGS2
SCHEMBL258596 0.93 THRA (0.47) THRATHRBLIPGALOX5PTGS2
SCHEMBL29829780 0.93 THRA (0.47) THRATHRBLIPGALOX5PTGS2
SCHEMBL570551 0.93 THRA (0.49) THRATHRBLIPGALOX5PTGS2
SCHEMBL14973628 0.87 THRA (0.52) THRATHRBLIPGALOX5PTGS2
SCHEMBL17353573 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL3997456 0.87 THRA (0.56) THRATHRBLIPGALOX5PTGS2
SCHEMBL8728298 0.87 THRA (0.52) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11473030-B2 Lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2022-10-18 US disclosed
US-20210214637-A1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-15 US disclosed
EP-3795663-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2021-03-24 EP disclosed
CN-112088206-A Lubricating oil composition 出光兴产株式会社 2020-12-15 CN disclosed
US-20160257902-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2016-09-08 US disclosed
EP-3064564-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2016-09-07 EP disclosed
US-9139795-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-09-22 US disclosed
EP-2428552-B1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2015-07-01 EP disclosed
US-8987177-B2 Biodegradable lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2015-03-24 US disclosed
US-20140296117-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2014-10-02 US disclosed
EP-2752480-A1 BIODEGRADABLE LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd (JP) 2014-07-09 EP disclosed
EP-2431450-B1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2014-05-07 EP disclosed
US-20140051618-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2014-02-20 US disclosed
EP-2067846-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2012-03-21 EP disclosed
EP-2431450-A1 BIODEGRADABLE LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120065111-A1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-03-15 US disclosed
EP-2428552-A1 BIODEGRADABLE LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2012-03-14 EP disclosed
US-20120053098-A1 BIODEGRADABLE LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-03-01 US disclosed
US-20100009880-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2010-01-14 US disclosed
EP-2067846-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2009-06-10 EP disclosed