SCHEMBL258596

SCHEMBL258596

CCCCc1ccccc1OP(=S)(Oc1ccccc1CCCC)Oc1ccccc1CCCC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
ALOX5 P09917 1/20 0.42
PTGS2 P35354 1/20 0.42
LIPG Q9Y5X9 1/20 0.40
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29829780 1.00 THRA (0.47) THRATHRBALOX5PTGS2LIPG
SCHEMBL31086340 0.93 THRA (0.55) THRATHRBALOX5PTGS2LIPG
SCHEMBL8600594 0.93 THRA (0.55) THRATHRBALOX5PTGS2LIPG
SCHEMBL284751 0.93 THRA (0.55) THRATHRBALOX5PTGS2LIPG
SCHEMBL1547923 0.93 THRA (0.55) THRATHRBALOX5PTGS2LIPG
SCHEMBL1604287 0.92 THRA (0.42) THRATHRBALOX5PTGS2PPARA
SCHEMBL258522 0.89 HTR1A (0.41) THRATHRBTAAR1
SCHEMBL29829807 0.89 HTR1A (0.41) THRATHRBTAAR1
SCHEMBL9821348 0.86 THRA (0.44) THRATHRBALOX5PTGS2LIPG
SCHEMBL2728772 0.86 THRA (0.48) THRATHRBALOX5PTGS2LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723276-B2 Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil NIPPON OIL CORPORATION (JP) 2010-05-25 US claimed
US-7696136-B2 Lubricant compositions containing hydroxy carboxylic acid and hydroxy polycarboxylic acid esters CROMPTON CORPORATION (US) 2010-04-13 US claimed
US-11946012-B2 Lubricating oil composition SHELL USA, INC. (US) 2024-04-02 US disclosed
US-20230002695-A1 LUBRICATING OIL COMPOSITION SHELL USA, INC. 2023-01-05 US disclosed
US-11254890-B2 Lubricant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
EP-3943583-A1 GREASE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2022-01-26 EP disclosed
WO-2021079976-A1 LUBRICATING OIL COMPOSITION FOR AUTOMOTIVE GEARS SHELL LUBRICANTS JAPAN K.K. (JP) 2021-04-29 WO disclosed
WO-2021064059-A1 NON-METALLIC PHOSPHORUS ANTIWEAR ADDITIVES CASTROL LIMITED (GB) 2021-04-08 WO disclosed
US-20210054299-A1 LUBRICANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2021-02-25 US disclosed
EP-2980194-B1 LUBRICANT OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2020-04-01 EP disclosed
US-10563148-B2 Lubricant oil composition IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
EP-1500693-A1 GREASE COMPOSITION Nippon Oil Corporation (JP) 2005-01-26 EP disclosed
EP-1500694-A1 GREASE COMPOSITION Nippon Oil Corporation (JP) 2005-01-26 EP disclosed
US-20040209786-A1 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NIPPON OIL CORPORATION (JP) 2004-10-21 US disclosed
US-20040116309-A1 Oil composition for cutting and grinding by minimal quantity lubrication system NIPPON OIL CORPORATION (JP) 2004-06-17 US disclosed
US-20040116308-A1 Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil NIPPON OIL CORPORATION (JP) 2004-06-17 US disclosed
EP-1405897-A1 TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE Nissan Motor Co., Ltd. (JP) 2004-04-07 EP disclosed
EP-1211302-B1 Refrigerating machine oil composition with carbon dioxide as refrigerant NIPPON MITSUBISHI OIL CORP (JP) 2003-08-06 EP disclosed
US-20020098993-A1 Refrigerating machine oil for carbon dioxide refrigerant and fluid composition for refrigerating machine NIPPON MITSUBISHI OIL CORPORATION 2002-07-25 US disclosed
EP-1211302-A1 Base oil for carbon dioxide refrigerant and refrigerating machine oil composition Nippon Mitsubishi Oil Corporation (JP) 2002-06-05 EP disclosed