SCHEMBL28475432

SCHEMBL28475432

O=C(C(=O)c1ccc(F)c(F)c1)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 15/20 0.79
CES1 P23141 15/20 0.79
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29798063 1.00 CES2 (0.79) CES2CES1RAB9ANPC1
SCHEMBL29798141 0.89 CES1 (1.00) CES2CES1RAB9ANPC1
SCHEMBL332679 0.83 ATM (0.61) CES2CES1RAB9ANPC1
SCHEMBL3556449 0.83 CES2 (0.78) CES2CES1RAB9ANPC1
SCHEMBL27905639 0.82 CES2 (0.56) CES2CES1RAB9A
SCHEMBL4784600 0.82 IDO1 (0.57) CES2CES1RAB9A
SCHEMBL4843572 0.81 CES2 (0.74) CES2CES1RAB9A
Benzil SCHEMBL4957522 0.79 CES2 (1.00) CES2CES1RAB9A
SCHEMBL1195835 0.79 CES2 (1.00) CES2CES1RAB9A
SCHEMBL5202387 0.78 CES2 (0.78) CES2CES1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848929-B Conjugated polymer of difluorophenyl substituted quinoxaline structural unit based on asymmetric structure and preparation method and application thereof 江苏理工学院 2022-08-19 CN claimed
CN-111848929-A Conjugated polymer of difluorophenyl substituted quinoxaline structural unit based on asymmetric structure and preparation method and application thereof 江苏理工学院 2020-10-30 CN claimed
CN-111848929-B Conjugated polymer of difluorophenyl substituted quinoxaline structural unit based on asymmetric structure and preparation method and application thereof 江苏理工学院 2022-08-19 CN disclosed
CN-111848929-A Conjugated polymer of difluorophenyl substituted quinoxaline structural unit based on asymmetric structure and preparation method and application thereof 江苏理工学院 2020-10-30 CN disclosed