Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.78 |
| ▸ | CES1 | P23141 | 5/20 | 0.78 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798141 | 0.88 | CES1 (1.00) | CES2CES1MEN1KMT2ACHRNA1 | |
| SCHEMBL12302152 | 0.83 | HDAC1 (0.61) | CES2CES1CPT1BKMT2ARAB9A | |
| SCHEMBL29798063 | 0.83 | CES2 (0.79) | CES2CES1RAB9ANPC1 | |
| SCHEMBL28475432 | 0.83 | CES2 (0.79) | CES2CES1RAB9ANPC1 | |
| SCHEMBL5202387 | 0.82 | CES2 (0.78) | CES2CES1MEN1KMT2ACHRNA1 | |
| SCHEMBL29349680 | 0.81 | CES2 (0.70) | CES2CES1MEN1KMT2ACHRNA1 | |
| SCHEMBL27151 | 0.81 | CES2 (0.70) | CES2CES1MEN1KMT2ACHRNA1 | |
| SCHEMBL15137054 | 0.81 | CES2 (0.52) | CES2CES1CPT1BMEN1KMT2A | |
| SCHEMBL10884738 | 0.81 | CES2 (0.52) | CES2CES1CPT1BRAB9ANPC1 | |
| SCHEMBL7162401 | 0.81 | CES2 (0.52) | CES2CES1CPT1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423394-B | Synthesis method of 1,3, 4-oxadiazole heterocyclic compound | 常州大学 | 2021-11-23 | — | — | CN | claimed |
| CN-111423394-B | Synthesis method of 1,3, 4-oxadiazole heterocyclic compound | 常州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-111423394-A | Synthesis method of 1,3, 4-oxadiazole heterocyclic compound | 常州大学 | 2020-07-17 | — | — | CN | disclosed |
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MSD K.K. (JP) | 2006-05-18 | — | — | US | disclosed |
| EP-1595867-A1 | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS CONTAINING PIPERIDINE DERIVATIVES AS THE ACTIVE INGREDIENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106046-A1 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | MCHR1, MC1R, PRLHR | CES2 1865/4885CES1 2157/4885CPT1B 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.