Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.78 |
| ▸ | DHODH | Q02127 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792945 | 0.88 | PLA2G2A (0.78) | PLA2G2ADHODHALDH1A1GAATP53 | |
| SCHEMBL6186359 | 0.86 | DHODH (0.85) | PLA2G2ADHODHKDM4EALDH1A1PTGES | |
| SCHEMBL26074099 | 0.86 | PLA2G2A (0.75) | PLA2G2ADHODHKDM4EALDH1A1GAA | |
| SCHEMBL28464923 | 0.85 | PLA2G2A (0.86) | PLA2G2ADHODHKDM4EALDH1A1PTGES | |
| SCHEMBL17923184 | 0.84 | MAPT (0.74) | PLA2G2ADHODHKDM4EALDH1A1CYP2C9 | |
| SCHEMBL27951590 | 0.84 | PLA2G2A (0.80) | PLA2G2ADHODHKDM4EALDH1A1PTGES | |
| SCHEMBL27938966 | 0.83 | PLA2G2A (0.78) | PLA2G2ADHODHKDM4EALDH1A1PTGES | |
| SCHEMBL20472457 | 0.82 | KDM4E (0.68) | PLA2G2ADHODHKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28693800 | 0.81 | KDM4E (0.72) | PLA2G2ADHODHKDM4EALDH1A1HPGD | |
| SCHEMBL26074118 | 0.79 | PLA2G2A (0.64) | PLA2G2ADHODHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336811-B | Preparation method of quinoline-4-formate compound | 浙江工业大学 | 2020-10-09 | — | — | CN | disclosed |