Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.78 |
| ▸ | DHODH | Q02127 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475970 | 0.88 | PLA2G2A (0.78) | PLA2G2ADHODHALDH1A1GAATP53 | |
| SCHEMBL5792900 | 0.86 | DHODH (0.78) | PLA2G2ADHODHALDH1A1GAAEPRS1 | |
| SCHEMBL26074099 | 0.86 | PLA2G2A (0.75) | PLA2G2ADHODHALDH1A1GAAMEN1 | |
| SCHEMBL27938966 | 0.85 | PLA2G2A (0.78) | PLA2G2ADHODHALDH1A1L3MBTL1TP53 | |
| SCHEMBL15919505 | 0.85 | EPRS1 (0.75) | PLA2G2ADHODHALDH1A1GAAL3MBTL1 | |
| SCHEMBL1901514 | 0.84 | PLA2G2A (0.73) | PLA2G2ADHODHALDH1A1GAAL3MBTL1 | |
| SCHEMBL28693800 | 0.81 | KDM4E (0.72) | PLA2G2ADHODHALDH1A1GAAL3MBTL1 | |
| SCHEMBL15905538 | 0.81 | PLA2G2A (0.56) | PLA2G2ADHODHALDH1A1L3MBTL1TP53 | |
| SCHEMBL26074102 | 0.79 | PLA2G2A (0.64) | PLA2G2ADHODHALDH1A1GAAL3MBTL1 | |
| SCHEMBL26074118 | 0.79 | PLA2G2A (0.64) | PLA2G2ADHODHALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034491-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006034512-A2 | PHENYL-SUBSTITUTED QUINOLINE AND QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |