SCHEMBL28476989

SCHEMBL28476989

Nc1cc(C(=O)O)ccc1-c1cc(-c2ccccc2)c(C(=O)O)c(-c2ccc(C(=O)O)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 6/20 0.52
EGFR P00533 2/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CHEK2 O96017 2/20 0.42
NPC1 O15118 1/20 0.42
HSP90AA1 P07900 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
TTR P02766 1/20 0.41
PTPRC P08575 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3098750 0.87 ALDH1A1 (0.53) MAP4K4ALDH1A1KDM4EGAAMAPT
Hydrochloric Acid SCHEMBL6619824 0.86 ALDH1A1 (0.51) MAP4K4ALDH1A1KDM4EGAAMAPT
Hydrochloric Acid SCHEMBL29064766 0.86 ALDH1A1 (0.51) MAP4K4ALDH1A1KDM4EGAAMAPT
SCHEMBL15901215 0.86 MAP4K4 (0.49) MAP4K4ALDH1A1KDM4EGAAMAPT
SCHEMBL30073619 0.84 MAP4K4 (0.51) MAP4K4EGFRKDM4EGAAHSD17B10
SCHEMBL26981140 0.84 KDM4E (0.50) MAP4K4ALDH1A1KDM4EGAAMAPT
SCHEMBL31207231 0.82 MAP4K4 (0.50) MAP4K4EGFRKDM4EGAAHSD17B10
SCHEMBL29152659 0.81 EGFR (0.51) MAP4K4EGFRKDM4EGAAHSD17B10
SCHEMBL17177739 0.81 KDM4E (0.50) ALDH1A1KDM4EGAAMAPTTHRB
SCHEMBL28682946 0.80 DHODH (0.57) MAP4K4EGFRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111804346-A Method for rapidly preparing metal organic layer material and application 中国人民解放军国防科技大学 2020-10-23 CN claimed