Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073619 | 0.98 | MAP4K4 (0.51) | MAP4K4KDM4EGAAHSD17B10SRD5A2 | |
| SCHEMBL26981140 | 0.98 | KDM4E (0.50) | MAP4K4KDM4EGAAHSD17B10SRD5A2 | |
| SCHEMBL31207231 | 0.96 | MAP4K4 (0.50) | MAP4K4KDM4EGAAHSD17B10SRD5A2 | |
| SCHEMBL8967952 | 0.92 | KDM4E (0.49) | MAP4K4KDM4EGAAHSD17B10SRD5A2 | |
| SCHEMBL29152659 | 0.91 | EGFR (0.51) | MAP4K4KDM4EGAAHSD17B10POLB | |
| SCHEMBL28866055 | 0.91 | HSD17B10 (0.53) | KDM4EGAAHSD17B10SRD5A2POLB | |
| SCHEMBL3098750 | 0.90 | ALDH1A1 (0.53) | MAP4K4KDM4EGAAHSD17B10SRD5A2 | |
| SCHEMBL31084440 | 0.90 | MAP4K4 (0.51) | MAP4K4KDM4EHSD17B10SRD5A2TP53 | |
| SCHEMBL13171608 | 0.90 | MAP4K4 (0.51) | MAP4K4KDM4EHSD17B10SRD5A2TP53 | |
| SCHEMBL31084444 | 0.90 | MAP4K4 (0.51) | MAP4K4KDM4EHSD17B10SRD5A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371444-B2 | Methods of making MOFs, systems for synthesizing MOFs, and methods of coating textiles with MOFs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-29 | — | — | US | claimed |
| CN-120040779-A | Azacyclo-carbene silver catalyst based on MOF framework and preparation method and application thereof | 华南理工大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119931239-A | Photo-thermal synergistic phase change composite film based on gradient carbon-based heterostructure and preparation method thereof | 山东理工大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119529305-A | Preparation method and application of amino-functionalized metal-organic framework material | 昭通学院 | 2025-02-28 | — | — | CN | claimed |
| CN-119303563-A | Catalyst for catalytic reduction of NOx and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-117624841-B | Basalt insulating composite material and application thereof in operating rod | 国网宁夏电力有限公司银川供电公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118725325-A | Method for improving freezing resistance of metal-organic framework and application of method in erythrocyte freezing protection | 华南理工大学 | 2024-10-01 | — | — | CN | claimed |
| US-20240294675-A1 | RING-OPENING METATHESIS POLYMERIZATION | THE TRUSTEES OF BOSTON COLLEGE (US) | 2024-09-05 | — | — | US | claimed |
| CN-118085312-A | Ionic liquid modified metal complex and preparation method and application thereof | 福州大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117701281-A | Metal-organic framework and fluoride nanocrystalline composite photon functional material and preparation method thereof | 浙江大学杭州国际科创中心 | 2024-03-15 | — | — | CN | claimed |
| CN-112961396-A | Preparation method of mould-proof high-strength expanded polystyrene heat-insulating material | 长沙三思新材料科技有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-112812387-A | Cold-resistant oil-resistant nitrile rubber for sealing element and preparation method thereof | 宁波市大器密封科技有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-213160784-U | Preparation device of multi-transition metal ion composite MOFs material | 武汉绿帆世纪科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-212770531-U | Preparation device with multi-level structure layer-by-layer coated MOFs (metal-organic frameworks) material | 武汉绿帆世纪科技有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-108070089-B | Preparation method of zirconium-based metal organic framework material rich in zirconium ions | 中国科学院大连化学物理研究所 | 2021-03-19 | — | — | CN | claimed |
| CN-112371108-A | Environment-friendly formaldehyde purification catalyst and preparation method thereof | 广州绿然环保新材料科技有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-111871465-A | Double-ligand metal organic framework photocatalyst and preparation method thereof | 苏州荣格君新材料有限公司 | 2020-11-03 | — | — | CN | claimed |
| US-9295982-B2 | MOF-based hierarchical porous materials and methods for preparation | BEIJING STAR NEW MATERIAL CO., LTD. (CN) | 2016-03-29 | — | — | US | claimed |
| EP-2878366-A1 | Mesoporous metal-organic frameworks with dominating interparticular porosity, methods for preparation thereof and uses | Beijing Star New Material Co., Ltd. (CN) | 2015-06-03 | — | — | EP | claimed |
| US-20140212944-A1 | MOF-based hierarchical porous materials, methods for preparation, methods for pore regulation and uses thereof | BEIJING STAR NEW MATERIAL CO., LTD. (CN) | 2014-07-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371444-B2 | Methods of making MOFs, systems for synthesizing MOFs, and methods of coating textiles with MOFs | PIEZO1, CUTA, MASTL | MAP4K4 98/4885KDM4E 245/4885GAA 3284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.