Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741875 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL3901283 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL8366738 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL7217491 | 0.84 | POLB (0.57) | SMN1; SMN2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL8366740 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL22402969 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL21552129 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL10161781 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTRAB9ANPC1HPGD | |
| SCHEMBL15689792 | 0.80 | ESR1 (0.65) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL3910015 | 0.80 | ESR1 (0.65) | RAB9ANPC1ESR1ESR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741956-A | Antiparasitic depsipeptides | 硕腾服务有限责任公司 | 2020-10-02 | — | — | CN | disclosed |