Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741875 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL8366738 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL28476992 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL8366740 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL22402969 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL21552129 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL10161781 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL7217283 | 0.81 | POLB (0.59) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL17202784 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1MAPTHPGD | |
| SCHEMBL17202644 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384511-B | Endoparasite depsipeptides | 硕腾服务有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| CN-111741956-B | Antiparasitic depsipeptides | 硕腾服务有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3790876-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| CN-112384511-A | Endoparasitic depsipeptides | 硕腾服务有限责任公司 | 2021-02-19 | — | — | CN | disclosed |
| EP-3717478-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
| WO-2019217449-A1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2019-11-14 | — | — | WO | disclosed |
| EP-0872481-B1 | DEPSIPEPTIDE DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND NOVEL INTERMEDIATE THEREFOR | ASTELLAS PHARMA INC (JP) | 2009-03-18 | — | — | EP | disclosed |
| CN-1162409-C | Depsipeptide deriv., its intermediate and method for preparing said intermediate | ����ҩƷ��ҵ��ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-0718293-B1 | CYCLODEPSIPEPTIDE COMPOUND | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-13 | — | — | EP | disclosed |
| CN-1071323-C | process for producing depsipeptide derivative or salt thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1309124-A | Depsipeptide deriv., its intermediate and method for preparing said intermediate | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-22 | — | — | CN | disclosed |
| EP-0872481-A1 | DEPSIPEPTIDE DERIVATIVE, PROCESS FOR PRODUCTION THEREOF, AND NOVEL INTERMEDIATE THEREFOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-21 | — | — | EP | disclosed |
| CN-1189159-A | Depsipeptide derivative, process for producing the same, and novel intermediate thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-07-29 | — | — | CN | disclosed |
| US-5646244-A | PARASITICIDES, ANTHELMINTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0718293-A1 | CYCLODEPSIPEPTIDE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | SMN1; SMN2 3040/4885RAB9A 549/4885NPC1 893/4885 |
| US-20200282016-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | SMN1; SMN2 3040/4885RAB9A 549/4885NPC1 893/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | SMN1; SMN2 3040/4885RAB9A 549/4885NPC1 893/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | SMN1; SMN2 3783/4885RAB9A 901/4885NPC1 1035/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | SMN1; SMN2 3040/4885RAB9A 549/4885NPC1 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.