Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 5/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507323 | 0.86 | L3MBTL1 (0.52) | BRD4NAMPTAKT1L3MBTL1HDAC1 | |
| SCHEMBL30504293 | 0.80 | HDAC1 (0.56) | BRD4NAMPTCREBBPGLSHDAC1 | |
| SCHEMBL31755970 | 0.79 | BRD4 (0.49) | BRD4NAMPTCREBBPGLSL3MBTL1 | |
| SCHEMBL4402738 | 0.79 | BRD4 (0.49) | BRD4NAMPTCREBBPGLSL3MBTL1 | |
| SCHEMBL301717 | 0.79 | PRMT6 (0.56) | BRD4NAMPTCREBBPGLSCYP2D6 | |
| SCHEMBL18664426 | 0.78 | HDAC1 (0.60) | BRD4CREBBPGLSHDAC1 | |
| SCHEMBL8279661 | 0.78 | POLB (0.53) | BRD4NAMPTCREBBPGLSCYP2D6 | |
| SCHEMBL16410240 | 0.77 | BRD4 (0.53) | BRD4CCKBRNAMPTCREBBPGLS | |
| SCHEMBL5869091 | 0.76 | RIPK2 (0.45) | RIPK2 | |
| SCHEMBL31754920 | 0.76 | GSK3B (0.53) | BRD4CCKBRNAMPTCREBBPGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069728-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111868063-B | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111868063-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2020-10-30 | — | — | CN | disclosed |