Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090062 | 0.91 | MEN1 (0.60) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6719484 | 0.86 | REN (0.46) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL9829903 | 0.84 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL27192643 | 0.82 | MEN1 (0.43) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6882714 | 0.78 | ALDH1A1 (0.79) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL30433983 | 0.78 | ALDH1A1 (0.79) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL6714618 | 0.76 | REN (0.47) | MEN1ALDH1A1KMT2AMAPTHRH3 | |
| SCHEMBL6720083 | 0.76 | CYP3A4 (0.46) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6713240 | 0.76 | CHRM2 (0.39) | MEN1ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6719956 | 0.76 | REN (0.46) | MAPTNPC1MAPK1RAB9ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936466-A | Compounds for the treatment of cardiac arrhythmias and heart failure | 埃利克斯生物技术公司 | 2020-11-13 | — | — | CN | disclosed |