Oxyquinoline

Oxyquinoline

SCHEMBL28477197

CC(C)O.Oc1cccc2cccnc12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.81
MMP2 P08253 2/20 0.81
METAP2 P50579 2/20 0.81
CHRM1 P11229 1/20 0.81
COMT P21964 1/20 0.81
ADRA1A P35348 1/20 0.81
METAP1 P53582 1/20 0.81
HDAC8 Q9BY41 1/20 0.81
KDM4E B2RXH2 7/20 0.68
ALOX12 P18054 3/20 0.68
LMNA P02545 3/20 0.58
ALDH1A1 P00352 2/20 0.58
PSMD14 O00487 1/20 0.52
COPS5 Q92905 1/20 0.52
MAPT P10636 3/20 0.50
HTT P42858 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
NFKB1 P19838 2/20 0.50
TP53 P04637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL9439888 0.93 TSHR (0.75) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL27529898 0.90 TSHR (0.91) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL37189 0.90 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 0.90 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL253313 0.90 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 0.90 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL10869516 0.88 TSHR (0.88) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.88 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21645991 0.88 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL20703753 0.88 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111926059-A Novel preservation solution for microbial nucleic acid in sputum 广州源古纪科技有限公司 2020-11-13 CN disclosed