SCHEMBL28477371

SCHEMBL28477371

O=Cc1cc2cccnc2c2ncccc12.O=Cc1cc2cccnc2c2ncccc12.O=Cc1cc2cccnc2c2ncccc12.[Ru]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 6/20 0.59
CCR8 P51685 6/20 0.59
L3MBTL1 Q9Y468 5/20 0.54
HSP90AA1 P07900 3/20 0.54
KDM4E B2RXH2 2/20 0.54
KMT2A Q03164 2/20 0.54
NPC1 O15118 2/20 0.54
MEN1 O00255 1/20 0.54
IDO1 P14902 1/20 0.54
RAB9A P51151 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
CCR5 P51681 4/20 0.52
ALDH1A1 P00352 3/20 0.51
MAPT P10636 2/20 0.51
LMNA P02545 2/20 0.45
CYP3A4 P08684 2/20 0.45
GMNN O75496 1/20 0.45
TP53 P04637 1/20 0.45
MMP2 P08253 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28476204 0.98 CCR1 (0.61) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL7749185 0.79 CCR1 (0.72) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL28461416 0.76 KDM4E (0.63) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL29957266 0.76 HSP90AA1 (0.54) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL12914331 0.75 L3MBTL1 (0.68) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL18788316 0.74 CCR1 (0.49) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL371564 0.74 CCR1 (1.00) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL3688928 0.74 L3MBTL1 (0.56) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL20798223 0.74 SLC40A1 (0.46) CCR1CCR8L3MBTL1HSP90AA1KDM4E
SCHEMBL18788338 0.73 CCR1 (0.51) CCR1CCR8L3MBTL1HSP90AA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109053814-B Fluorescent probe ruthenium complex, and synthesis method and application thereof 湖南文理学院 2020-10-27 CN disclosed