Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496653 | 0.83 | LMNA (0.44) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL9260647 | 0.81 | LMNA (0.48) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL14120803 | 0.79 | CYP11B1 (0.57) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL21654018 | 0.78 | ALDH1A1 (0.44) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL16562332 | 0.76 | ALDH1A1 (0.51) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL16437249 | 0.76 | CYP11B1 (0.57) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| Methoxymethane SCHEMBL8588766 | 0.74 | LMNA (0.47) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL29285330 | 0.73 | LMNA (0.37) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL270275 | 0.73 | MAPT (0.58) | LMNAALDH1A1CYP3A4KMT2AMAPT | |
| SCHEMBL16559756 | 0.73 | ALDH1A1 (0.55) | LMNAALDH1A1CYP3A4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108499606-B | O-mercapto aryl nitrogen heterocyclic carbene metal complex catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-11-20 | — | — | CN | disclosed |